TB500

Research Peptide | 5 mg Lyophilized Vial

UPA TB-500 is a synthetic analogue of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide found in nearly all human and animal cells. TB-500 is extensively studied for its role in tissue repair, angiogenesis, inflammation modulation, and cellular migration.

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Key Research-Observed Functions

• Promotes cell migration and tissue regeneration

• Supports angiogenesis and endothelial cell differentiation

• Stimulates myoblast and myocyte activity

• Reduces inflammation and oxidative stress

• Supports collagen deposition and connective tissue remodeling

• Regulates actin dynamics (F-actin binding)

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Research Highlights

• Cardiac repair: Preclinical studies show TB-500 supports myocardial cell survival, vascular growth, and repair following injury

• Muscle regeneration: Increased local expression following muscle damage; supports skeletal muscle healing and fiber regeneration

• Respiratory research: Demonstrated actin-modulating effects that reduce mucus viscosity in cystic fibrosis models

• Dermal repair: Supports keratinocyte migration and wound healing pathways

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TB-500 dosage and cycle duration:

Dosage depends on the purpose and severity of the injury / damage you are treating. People generally use between 4 to 8 mg of TB500 per week during the initial (loading) period of 4 to 6 weeks. Afterwards some opt to maintain the effects with a low 2 to 6 mg dose once every 2 weeks. The effects of TB-500 wear off within 2 – 3 weeks of injection.

1. TB-500 loading phase:

duration: between 4 – 6 weeks

dosage: between 4 – 8 mg of TB-500 per week

frequency of injection:2 mg per injection, between 2 – 4 times per week (depending on the total weekly dosage)

2. TB-500 maintainance phase:

duration: as long as needed

dosage: between 2 – 6 mg of TB-500 per 2 weeks

frequency of injection:2 mg per injection, between 2 – 3 times per 2 weeks (depending on the total bi-weekly dosage)